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sickle for Mac

Windowed adaptive trimming for FASTQ files using quality

Quick answer: sickle is a command-line tool for macOS. Install it with brew install sickle. It is distributed under the MIT licence.

What sickle is

sickle is a command-line tool for macOS: windowed adaptive trimming for FASTQ files using quality.

It is distributed as a Homebrew formula, which builds or pours a binary and puts it on your PATH. The project is open source and lives at https://github.com/najoshi/sickle.

How to install sickle

  1. Open Terminal (press ⌘ + Space and type “Terminal”).
  2. If Homebrew is not installed yet, run the installer below once.
  3. Run brew install sickle.

Homebrew installer, if you need it:

Prefer a graphical installer? Download it from the official site. MacPicks never hosts or mirrors binaries — the Homebrew command always pulls from the vendor's own release.

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Frequently asked questions

How do I install sickle on Mac?

Run brew install sickle in Terminal. This requires Homebrew; if you do not have it, install it first with the command below.

Is sickle open source?

Yes — Homebrew distributes it under the MIT licence.

Does sickle run on Apple silicon?

Homebrew publishes this formula for macOS. If upstream does not ship an Apple silicon build, Rosetta 2 handles the Intel binary.

How popular is sickle?

Homebrew does not publish a 30-day install count for this package, which usually means it is installed directly rather than through the analytics-reporting path.

What version of sickle is current?

The latest packaged version is 1.33.